Evidence map›Paper›PMID 42864367›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Long-term outcomes of preterm infants admitted to single-family rooms versus an open-bay neonatal intensive care unit: A randomized controlled trial.

Michael J Vincer, Christy G Woolcott, Darlene J Inglis, Tanya M Myles, Susan M MacDonald, Jehier Afifi, C David Simpson, Satvinder Ghotra, Walid El-Naggar, Balpreet Singh and 5 more

Registry-linked trialAbstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03867669 (Neurodevelopmental Outcomes at Three Years of Age in Very Preterm Infants), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03867669 naunknown statusnot on this map

Neurodevelopmental Outcomes at Three Years of Age in Very Preterm Infants (< 31 Weeks Gestational Age) or Very Low Birth Weight (< 1500 Grams) Randomized to Single Patient Rooms Compared to Open Bay Neonatal Intensive Care Unit

TypeinterventionalSponsorIWK Health CentreRan2018 to 2023Enrolled160ConditionsNeurodevelopmental OutcomesArmsOpen Bay Unit, Single patient room
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Michael J VincerDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada. vincer@dal.ca.ORCID http://orcid.org/0000-0001-8119-3286
Christy G WoolcottDepartments of Pediatrics and Obstetrics & Gynecology, Perinatal Epidemiology Unit, Dalhousie University, Halifax, NS, Canada.
Darlene J InglisDepartment of Nursing, Izaak Walton Killam Health, Halifax, NS, Canada.
Tanya M MylesDepartment of Nursing, Izaak Walton Killam Health, Halifax, NS, Canada.
Susan M MacDonaldDepartment of Nursing, Izaak Walton Killam Health, Halifax, NS, Canada.
Jehier AfifiDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.ORCID http://orcid.org/0000-0001-7651-3054
C David SimpsonDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.ORCID http://orcid.org/0000-0003-0975-897X
Satvinder GhotraDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.ORCID http://orcid.org/0000-0002-9703-9918
Walid El-NaggarDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.ORCID http://orcid.org/0000-0001-6657-4507
Balpreet SinghDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Danielle StyrankoDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Sharon UngerDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Souvik MitraDepartment of Pediatrics, University of British Columbia, British Columbia, Vancouver, BC, Canada.
Douglas D McMillanDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Jon S DorlingChild Health Outcomes Research At Leeds, University of Leeds, Leeds, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare long-term outcomes of preterm infants in single-family room (SFR) vs. open-bay (OB) neonatal intensive care unit (NICU). STUDY

designThis randomized controlled trial took place in a tertiary NICU from April 2018 to June 2019. Infants <31 weeks gestation or ≤1500 grams birthweight were randomly assigned upon admission to SFR or OB. The primary outcome was death or neurodevelopmental impairment (NDI; cerebral palsy, language delay, cognitive delay, blindness, or deafness) at 36 months corrected age. Secondary outcomes were mortality, NDI components, and safety measures.

resultsOf 85 infants (43 SFR, 42 OB), there was no difference in primary outcome (40.5% SFR vs. 47.4% OB, p = 0.644). Secondary outcomes did not differ except mortality, which was lower in SFR (1/41, 2.4%) than OB (8/42, 19.0%), p = 0.029.

conclusionsComposite outcome of death/NDI at 36 months corrected age was similar; however, reduction in mortality was noted in SFR. This trial was registered 6 Mar 2019 with ClinicalTrials.gov, NCT03867669 ( https://clinicaltrials.gov/search?cond=NCT03867669 ).

Identifiers

PMID42864367

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.