ArticleCartilage2026
Baseline Knee Extension Is Associated With Volumetric Femoral Cartilage Loss in the Central Region of the Mid-lateral and External Medial Femoral Condyles: Data From the Osteoarthritis Initiative.
Article in Cartilage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
ObjectiveData evaluating knee flexion contracture (FC)-associated regional changes on femoral articular cartilage are lacking. We compared regional femoral articular cartilage outcomes of people with knee osteoarthritis (OA) with and without FC using quantitative MRI data.MethodsArticular cartilage of the medial and lateral femoral condyles were segmented into internal, central, and external subregions on MRI. Goniometry measured knee extension. We tested for regional differences in cartilage thickness and percent denuded bone (i.e., 0mm cartilage thickness) in the presence or absence of FC, and for associations between cartilage outcomes with quantitative knee extension range of motion (ROM) using a linear model for 596 participants.ResultsFor FC versus no FC, cartilage thickness in the central lateral subregion was higher (2.36±0.42mm vs. 2.29±0.43mm; p<0.05), with higher percent denuded bone in the central lateral (0.92±3.5% vs. 0.39±2.2%; p<0.05) and central medial subregions (4.61±12.88% vs. 3.17±11.66%; p<0.05). Lost knee extension was associated with increased percent denuded bone in the internal lateral (
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