Evidence map›Paper›PMID 42863062›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

P-body-mediated RNA decay controls neural crest EMT.

Arvind Arul Nambi Rajan, Michael L Piacentino, Marianne E Bronner, Erica J Hutchins

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arvind Arul Nambi RajanDepartment of Cell and Tissue Biology, University of California San Francisco, San Francisco, CA 94143.
Michael L PiacentinoDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
Marianne E BronnerDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.ORCID 0000-0003-4274-1862
Erica J HutchinsDepartment of Cell and Tissue Biology, University of California San Francisco, San Francisco, CA 94143.ORCID 0000-0002-4316-0333

Funding

Cell lineage and transcriptional analysis of the vertebrate neural plate borderR01DE027538 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Marianne Bronner · 2018 to 2026
$4.4M
Gene Regulatory Network Controlling Premigratory Cranial vs Trunk Neural CrestR01DE024157 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BRONNER, MARIANNE · 2014 to 2025
$4.0M
Mechanisms of RNA turnover during the epithelial-mesenchymal transitionR35GM150763 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Erica Hutchins · 2023 to 2026
$1.6M
Characterization of the roles and regulation of Draxin in cranial neural crestR00DE028592 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUTCHINS, ERICA · 2022 to 2024
$1.1M
Characterizing the cranial neural crest response to BMP signaling through gastrulation and neurulationR00DE029240 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI PIACENTINO, MICHAEL LOUIS · 2023 to 2025
$873k
HHS | NIH | National Institute of Dental and Craniofacial Research (NIDR) DE024157HHS | NIH | National Institute of Dental and Craniofacial Research (NIDR) DE027538HHS | NIH | National Institute of Dental and Craniofacial Research (NIDR) R00DE028592HHS | NIH | National Institute of Dental and Craniofacial Research (NIDR) R00DE029240HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM150763NIDCR NIH HHS R00 DE028592NIDCR NIH HHS R00 DE029240NIDCR NIH HHS R01 DE024157NIDCR NIH HHS R01 DE027538NIGMS NIH HHS R35 GM150763
6 · The paper itself

Abstract

Neural crest cells, a multipotent vertebrate stem cell population, undergo a tightly regulated epithelial-mesenchymal transition (EMT) to delaminate from the neural tube and initiate migration. Neural crest EMT is controlled by a transient pulse of

Indexed as

Epithelial-Mesenchymal TransitionNeural CrestRNA Stability3' Untranslated RegionsAnimalsDEAD-box RNA HelicasesGene Expression Regulation, DevelopmentalHumansProto-Oncogene ProteinsRNA, Messenger3' Untranslated RegionsDDX6 protein, humanDEAD-box RNA HelicasesProto-Oncogene ProteinsRNA, MessengerEMTepithelial to mesenchymal transitionneural crestP-bodiesposttranscriptional regulation

Identifiers

PMID42863062
PMCPMC13681325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.