Evidence map›Paper›PMID 42862859›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2026

Premotor cortices differentially influence contralateral motor cortex.

Elnaz Allahverdloo, Larissa K Chiu, Amanda O'Farrell, Nesrine Harroum, Numa Dancause, Jason L Neva

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elnaz AllahverdlooCentre de recherche de l'institut universitaire de gériatrie de Montréal (CRIUGM), 4545 chemin Queen-Mary, Montréal, Québec H3W 1W4, Canada.
Larissa K ChiuCentre de recherche de l'institut universitaire de gériatrie de Montréal (CRIUGM), 4545 chemin Queen-Mary, Montréal, Québec H3W 1W4, Canada.ORCID 0000-0002-9370-7157
Amanda O'FarrellCentre de recherche de l'institut universitaire de gériatrie de Montréal (CRIUGM), 4545 chemin Queen-Mary, Montréal, Québec H3W 1W4, Canada.
Nesrine HarroumCentre de recherche de l'institut universitaire de gériatrie de Montréal (CRIUGM), 4545 chemin Queen-Mary, Montréal, Québec H3W 1W4, Canada.ORCID 0000-0003-2684-9785
Numa DancauseDépartement de neurosciences, Faculté de médecine, Université de Montréal, Pavillon Paul-G.-Desmarais, 2960, chemin de la Tour, Montréal, Québec H3T 1J4, Canada.
Jason L NevaCentre de recherche de l'institut universitaire de gériatrie de Montréal (CRIUGM), 4545 chemin Queen-Mary, Montréal, Québec H3W 1W4, Canada.ORCID 0000-0002-8211-9923

Funding

Canadian Foundation for InnovationCentre Interdisciplinaire de Recherche sur le Cerveau et l'ApprentissageSoutien aux initiatives de recherche interdisciplinaireUniversité de Montréal
6 · The paper itself

Abstract

Dorsal (PMd) and ventral (PMv) premotor cortices can modulate contralateral primary motor cortex (M1) excitability, but their distinct interhemispheric influence via transcranial magnetic stimulation (TMS) remains unclear. Single-pulse TMS over PMd, PMv and M1 assessed transcallosal inhibition via the ipsilateral silent period (iSP). Dual-site TMS examined short-(10 ms inter-stimulus interval [ISI]), long-(50 ms ISI) and non-callosal-(0 ms ISI) interhemispheric inhibition (IHI). An iSP was elicited from PMd, PMv, and M1, with distinctly evoked iSP parameters. The iSP magnitude was greatest from M1, followed by PMd and then PMv, while iSP duration was greatest for M1 and showed no differences between PMd and PMv. Dual-site TMS revealed that PMd and M1 inhibited contralateral M1 excitability across all ISIs, while PMv showed inhibition at 0- and 50-ms ISIs. PMd and M1 demonstrated greater short-IHI compared to PMv, all demonstrating similar long-IHI, and PMd demonstrating greater non-callosal-IHI than M1. PMv displayed distinct IHI across ISIs, PMd showed differences across most ISIs and M1 demonstrated the fewest differences across ISIs. Longer iSP duration related to greater long-IHI magnitude elicited from PMd and PMv. Our findings demonstrate differential IHI from PMd and PMv on contralateral M1, which may inform neuromodulation strategies in rehabilitation contexts.

Indexed as

Evoked Potentials, MotorFunctional LateralityMotor CortexNeural InhibitionAdultCorpus CallosumElectromyographyFemaleHumansMaleTranscranial Magnetic StimulationYoung Adultdorsal/ventral premotor cortexinterhemispheric inhibitionipsilateral silent periodprimary motor cortextranscranial magnetic stimulation

Identifiers

PMID42862859
PMCPMC13657042

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.