Evidence map›Paper›PMID 42862491›Full record

ReviewMycotoxin research2026

Biological detoxification of Ochratoxin A: current status, mechanisms, and applications.

Zhuoxiao Li, Qin Ding, Tongtong Liu, Juan Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mycotoxin research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhuoxiao LiSchool of Public Health, Key Laboratory of Environmental Medicine Engineering Ministry of Education, Southeast University, Nanjing, 210009, China.
Qin DingSchool of Public Health, Key Laboratory of Environmental Medicine Engineering Ministry of Education, Southeast University, Nanjing, 210009, China.
Tongtong LiuSchool of Public Health, Key Laboratory of Environmental Medicine Engineering Ministry of Education, Southeast University, Nanjing, 210009, China.
Juan ZhangSchool of Public Health, Key Laboratory of Environmental Medicine Engineering Ministry of Education, Southeast University, Nanjing, 210009, China. zhangjuan@seu.edu.cn.

Funding

China Postdoctoral Science Foundation funded project 2024M760442Postdoctoral Fellowship Program of CPSF GZC20240246the National Nature Science Foundation of China 82404225
6 · The paper itself

Abstract

Ochratoxin A (OTA) is a chemically stable and ubiquitous mycotoxin that poses persistent threats to environmental safety and public health due to its potent nephrotoxicity and carcinogenicity. Given the limitations of conventional physical and chemical remediation, biological detoxification has emerged as a sustainable and high-efficiency alternative. This review systematically evaluates three core biological strategies: biological inhibition via nutrient competition and metabolic interference; biosorption through non-covalent binding by microbial cell wall components; and biodegradation, focusing on the enzymatic cleavage of the amide bond or lactone ring. We highlight recent breakthroughs in OTA- degrading enzymes, such as carboxypeptidases and amidohydrolases, emphasizing their catalytic pathways and potential for recombinant expression. Furthermore, the practical applications, industrial challenges, and safety considerations of these green technologies are discussed. This work provides a comprehensive theoretical framework for developing eco-friendly and targeted strategies to safeguard the global food chain and mitigate environmental mycotoxin contamination.

Indexed as

OchratoxinsBiodegradation, EnvironmentalInactivation, MetabolicMycotoxinsMycotoxinsochratoxin AOchratoxinsBiodegradationBiological detoxificationBiosorptionDetoxification mechanismDetoxifying enzymesOchratoxin APollution status

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.