Evidence map›Paper›PMID 42862451›Full record

ReviewIrish journal of medical science2026

Neonatal appendicitis with rectal bleeding: an unusual presentation.

Sinan Kılıç, Şenol Bozdağ, Murat Cengiz Aşıcıoğlu, B Haluk Güvenç

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Review in Irish journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sinan KılıçDepartment of Pediatric Surgery, Faculty of Medicine, Istanbul Okan University, Istanbul, Turkey. dr.sinankilic@yahoo.com.ORCID http://orcid.org/0000-0003-3454-5538
Şenol BozdağDepartment of Pediatrics, Faculty of Medicine, Istanbul Okan University, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-0016-346X
Murat Cengiz AşıcıoğluDepartment of Pediatric Surgery, Faculty of Medicine, Istanbul Okan University, Istanbul, Turkey.ORCID http://orcid.org/0009-0000-3842-1458
B Haluk GüvençDepartment of Pediatric Surgery, Faculty of Medicine, Istanbul Okan University, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-8025-1747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeonatal appendicitis is an exceptionally rare condition with a high risk of delayed diagnosis and perforation. Its nonspecific clinical presentation may mimic other causes of acute abdomen and gastrointestinal bleeding in newborns, particularly necrotizing enterocolitis. CASE PRESENTATION: A 36-week, 2500-g male neonate developed abdominal distension, irritability, decreased oral intake, and bright red rectal bleeding on the second day of life. Abdominal radiography demonstrated multiple air-fluid levels, while ultrasonography revealed dilated bowel loops and free intraperitoneal fluid. Exploratory laparotomy revealed a hyperaemic, oedematous, and indurated appendix with localized inflammatory changes, without perforation or gangrenous changes. Appendectomy was performed, and histopathological examination confirmed acute appendicitis with transmural inflammation and fibrinous exudates, without necrosis or histopathological findings suggestive of necrotizing enterocolitis. The patient recovered uneventfully, and no further rectal bleeding was observed after appendectomy.

conclusionNeonatal appendicitis should be considered in the differential diagnosis of newborns presenting with hematochezia, particularly when rectal bleeding is accompanied by abdominal distension and signs of intestinal obstruction or ileus. Although the condition is rare and its clinical presentation is nonspecific, recognition of atypical presentations may facilitate timely surgical evaluation and treatment.

Indexed as

Acute appendicitisAppendectomyHematocheziaNecrotizing enterocolitis

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.