ReviewMolecular biology reports2026
Trogocytosis: Emerging insights into cellular communication, immunity, and pathogenesis.
Review in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trogocytosis is a unique intercellular process that can occur when two cells become in contact to each other and one cell "nibbles" portions of another cell's membrane and surface molecules. This phenomenon is widely observed among immune cells such as B cells, T cells, NK cells, and antigen-presenting cells (APCs). Through trogocytosis, molecules including major histocompatibility complexes (MHC), costimulatory receptors, and antigens are transferred, influencing cellular communication and immune regulation. While trogocytosis supports processes like antigen presentation, immune activation, and neural remodeling, it also contributes to pathological conditions, including tumor immune evasion, therapeutic resistance, and pathogen dissemination. This duality raises critical questions about its overall impact: is trogocytosis a friend or foe to the immune system? By comparing trogocytosis to phagocytosis, exploring molecular mechanisms, and examining its roles in health and disease, this review synthesizes current findings and highlights areas for future investigation. Understanding the precise mechanisms governing trogocytosis could pave the way for innovative therapies targeting infections, cancers, and autoimmune disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.