Evidence map›Paper›PMID 42862307›Full record

ArticleEuropean journal of applied physiology2026

Sex- and condition-dependent muscle oxygenation, performance fatigability, and post-occlusive reactive hyperemic responses to blood flow restriction exercise.

Minyoung Kwak, Brian Benitez, Clara J Mitchinson, Erik R Snell, Alaina N Kuhn, Michael A Samaan, Timothy Butterfield, Ashley Samson, Patrick Pabian, Haley C Bergstrom

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Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Minyoung KwakDepartment of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY, 40506, USA. mkwak8@jh.edu.ORCID http://orcid.org/0009-0003-8617-2611
Brian BenitezDepartment of Health Sciences, Stetson University, DeLand, FL, 32723, USA.
Clara J MitchinsonDepartment of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY, 40506, USA.
Erik R SnellDepartment of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY, 40506, USA.
Alaina N KuhnDepartment of Nutrition and Health Sciences, University of Nebraska- Lincoln, Lincoln, NE, 68583, USA.
Michael A SamaanDepartment of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY, 40506, USA.
Timothy ButterfieldDepartment of Athletic Training and Clinical Nutrition, University of Kentucky, Lexington, KY, 40536, USA.
Ashley SamsonDepartment of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY, 40506, USA.
Patrick PabianDepartment of Physical Therapy, University of Kentucky, Lexington, 40536, KY, USA.
Haley C BergstromDepartment of Nutrition and Health Sciences, University of Nebraska- Lincoln, Lincoln, NE, 68583, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study examined sex- and condition-dependent differences in muscle oxygenation, performance fatigability (PF), and post-occlusive reactive hyperemic responses during moderate-pressure (40% of arterial occlusion pressure) blood flow restriction exercise (BFR), free-flow exercise (NON-BFR), and BFR without exercise (PASSIVE BFR).

methodsFifteen males and fourteen females completed all three conditions in a randomized crossover design. Exercise consisted of unilateral, dynamic leg extensions performed at 30% of maximal voluntary isometric contraction (MVIC) using a 30-15-15-15 repetition protocol with 60-s inter-set recovery periods. During intervention and recovery sets, muscle oxygenation (SmO

resultsCompared with NON-BFR and PASSIVE BFR, BFR elicited lower SmO

conclusionAlthough BFR induced marked intramuscular deoxygenation and greater fatigability in both sexes, we did not detect a corresponding enhancement in post-exercise reactive hyperemic response, a finding that should be interpreted cautiously given the limited reliability of Slope 2.

Indexed as

Blood flow restrictionMuscle oxygenationNear-Infrared spectroscopyPost-occlusive reactive hyperemiaVascular occlusion test

Identifiers

PMID42862307

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.