Evidence map›Paper›PMID 42861656›Full record

ReviewThe Journal of antimicrobial chemotherapy2026

Oxazolidinones in the Clinical Management of Staphylococcal Infection-Linezolid or Tedizolid? A review on behalf of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Staphylococci and Staphylococcal Diseases (ESGS).

Liana Macpherson, Anne-Grete Martson, Jose L Del Pozo, Cindy Zheng, Anna L Goodman

Abstract readReview
In one paragraph

Review in The Journal of antimicrobial chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liana MacphersonDepartment of Infection, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0001-6025-0878
Anne-Grete MartsonEuropean Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Staphylococci and Staphylococcal Diseases (ESGS).
Jose L Del PozoEuropean Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Staphylococci and Staphylococcal Diseases (ESGS).
Cindy ZhengDepartment of Infection, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Anna L GoodmanDepartment of Infection, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0003-0643-9017

Funding

Medical Research Council MC_UU_00004/05National Institute of Health and Care Research NIHR133719
6 · The paper itself

Abstract

There is limited information in the existing literature regarding the choice of oxazolidinone in clinical practice to treat infections caused by staphylococcal species. As members of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Staphylococci and Staphylococcal Diseases (ESGS) we have collaborated and written this narrative review aimed at clinicians considering these agents in practice. The review focuses on two medications, linezolid and tedizolid, with a comprehensive description of pharmacology aspects, adverse effects, drug interactions and contraindications, and we investigate the potential for treatment optimization. We anticipate that this article will provide support for those considering utilization of linezolid and tedizolid in clinical practice to treat staphylococcal species.

Indexed as

Anti-Bacterial AgentsLinezolidOxazolidinonesStaphylococcal InfectionsStaphylococcusTetrazolesDrug InteractionsEuropeHumansAnti-Bacterial AgentsLinezolidOxazolidinonestedizolidTetrazoles

Identifiers

PMID42861656
PMCPMC13655609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.