ArticleSexually transmitted diseases2026
Associations Between Maternal Mental Health and Congenital Syphilis Birth Outcomes: Analysis of Georgia Surveillance Data, 2018-2023.
Article in Sexually transmitted diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundCongenital syphilis (CS) is a preventable yet persistent public health problem in the United States. Maternal mental health conditions (MMHC) during pregnancy may contribute to missed prevention opportunities, but their association with CS outcomes is unclear.
methodsGeorgia sexually transmitted infections (STI) surveillance data (2018-2023) were analyzed to assess prebirth MMHC mentions among syphilis-affected pregnancies, their association with CS, and variation by maternal household composition as a proxy for immediate social support. MMHC mentions were identified using rule-based analysis of free-text case narratives from the year before delivery. Modified Poisson regression was used to estimate adjusted prevalence ratios (aPR), and an internal validation substudy informed probabilistic bias adjustment for MMHC misclassification.
resultsAmong 1684 syphilis-affected pregnancies, 416 (25%) resulted in CS. Prebirth MMHC were documented in 4% and were associated with higher CS prevalence (aPR, 1.5; 95% confidence interval [CI], 1.1-2.1). Although the association did not differ significantly by maternal household composition, it was attenuated among women living with family or partners (aPR, 1.18; 95% CI, 0.57-2.47) compared with those living alone or with nonfamily members (aPR, 1.42; 95% CI, 0.70-2.90). Internal validation indicated MMHC under-ascertainment in surveillance data; bias-adjusted analyses suggested a stronger association with CS, albeit with considerable uncertainty (bias-adjusted PR, 2.1; 95% simulation interval, 0.8-5.0).
conclusionsPrebirth MMHC mentions captured during STI case investigations were associated with increased CS prevalence and may serve as an early indicator of vulnerability. Incorporating mental health-informed follow-up into STI surveillance workflows could enhance care coordination and strengthen CS prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.