In one paragraphArticle in Circulation. Cardiovascular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
19 authors.
Harpreet S BhatiaDivision of Cardiology, Department of Medicine, University of California San Diego Health, La Jolla (H.S.B., M.C.).ORCID 0000-0002-3964-2989 Alexander C RazaviEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA (A.C.R.).ORCID 0000-0002-3213-0876 Zeina DardariJohns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD (Z.D., M.J.B.).ORCID 0000-0001-6026-3329 David R JacobsDivision of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis (D.R.J.).ORCID 0000-0002-7232-0543 James G TerryDepartment of Radiology, Vanderbilt University Medical Center, Nashville, TN (J.G.T., J.J.C.).ORCID 0000-0001-6659-3441 J Jeffrey CarrDepartment of Radiology, Vanderbilt University Medical Center, Nashville, TN (J.G.T., J.J.C.).ORCID 0000-0002-4398-8237 Daniel DuprezCardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis (D.D.).ORCID 0000-0002-0993-6839 Parag H JoshiDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas (P.H.J., A.R., A.K.).ORCID 0000-0001-7863-2794 Anand RohatgiDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas (P.H.J., A.R., A.K.).ORCID 0000-0003-0164-2382 Amit KheraDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas (P.H.J., A.R., A.K.).ORCID 0000-0001-7255-6874 Jamal S RanaDepartment of Cardiology, Kaiser Permanente Oakland Medical Center, CA (J.S.R.).
Tara S AllenDepartment of Medicine, San Diego VA Healthcare System, La Jolla, CA (T.S.A.).
Julie DenenbergDivision of Preventive Medicine, Department of Family Medicine, University of California, San Diego, La Jolla (J.D., M.A., M.C.).
Matthew BudoffDivision of Cardiology, Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA (M.B.).ORCID 0000-0002-9616-1946 Matthew AllisonDivision of Preventive Medicine, Department of Family Medicine, University of California, San Diego, La Jolla (J.D., M.A., M.C.).ORCID 0000-0003-0777-8272 Michael J BlahaJohns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD (Z.D., M.J.B.).ORCID 0000-0001-5138-9683 Michael CriquiDivision of Cardiology, Department of Medicine, University of California San Diego Health, La Jolla (H.S.B., M.C.).ORCID 0000-0003-0425-9661 Funding
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1MWake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3MClinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2MUT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5MTask Area A Core Study Operations.Task Area A shall encompass annual follow-up of cohort members, clinical endpoints ascertainment, study coordination activities, maintenance of the database and biosp75N92020D00001 · NHLBI · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, ROBYN LEAGH · 2020 to 2025
$17.2MUC San Diego Clinical and Translational Research InstituteKL2TR001444 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2024
$15.4MCORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - COORDINATING CENTER (CC)75N92023D00002 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LI, JING · 2023 to 2025
$6.8MUCSD Integrated Cardiovascular Epidemiology FellowshipT32HL079891 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Matthew A Allison · 2007 to 2026
$6.7MTask Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00005 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2020 to 2025
$5.1MLongitudinal Changes in Pericardial Adiposity and Subclinical AtherosclerosisR01HL098445 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CARR, JOHN JEFFREY · 2010 to 2013
$4.6MTO EXERCISE OPTION PERIOD ONE (1) FOR TASK AREA A - MESA CORE OPERATIONS, FIELD CENTER.75N92020D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI SIEGEL, JONATHAN H · 2020 to 2025
$4.5MTask Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI PANKOW, JAMES S · 2020 to 2025
$4.4MNCATS NIH HHS KL2 TR001444NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001105NCATS NIH HHS UL1 TR001420NHLBI NIH HHS 75N92020D00001NHLBI NIH HHS 75N92020D00002NHLBI NIH HHS 75N92020D00003NHLBI NIH HHS 75N92020D00004NHLBI NIH HHS 75N92020D00005NHLBI NIH HHS 75N92020D00006NHLBI NIH HHS 75N92020D00007NHLBI NIH HHS 75N92023D00002NHLBI NIH HHS 75N92023D00003NHLBI NIH HHS 75N92023D00004NHLBI NIH HHS 75N92023D00005NHLBI NIH HHS 75N92023D00006NHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS K08 HL166962NHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL098445NHLBI NIH HHS R01 HL116395NHLBI NIH HHS T32 HL079891
6 · The paper itselfAbstract
backgroundCoronary artery calcium (CAC) scoring is a useful tool for coronary heart disease (CHD) risk prediction. The current standard method, the Agatston score, weights plaque area upward by density. However, higher density is inversely associated with CHD. We aimed to develop and validate a CAC score accounting for the inverse association of density with CHD, and the nonlinear association between CAC volume and density in a prospective cohort study.
methodsA CAC volume and density score was developed, which adjusts CAC volume for density based on whether the volume level was <130 mm
resultsThe MESA cohort included 3360 individuals. CAC volume and density score improved the
conclusionsThe CAC volume and density score, which adjusts CAC volume downward for higher density, and can be calculated from existing CAC reports, significantly improves risk discrimination and reclassification compared with the Agatston score.
Indexed as
aspirinblood pressurecardiovascular diseasesdemographyprimary prevention
Identifiers
PMID42861496
PMCPMC13667856
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