Evidence map›Paper›PMID 42861453›Full record

ArticleBioMed research international2026

Medicinal Use of Lepidium sativum and Nigella sativa Seeds in North Shewa Zone, Amhara and Oromia Regions, Ethiopia.

Daniel Molla Melese, Wondyefraw Mekonen, Abebaye Aragaw

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Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Daniel Molla MeleseDepartment of Biomedical Science, Asrat Woldeyes Health Science Campus, Debre Berhan University, Debre Berhan, Ethiopia, dbu.edu.et.ORCID https://orcid.org/0000-0002-1277-2986
Wondyefraw MekonenDepartment of Physiology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia, aau.edu.et.
Abebaye AragawDepartment of Physiology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia, aau.edu.et.ORCID https://orcid.org/0000-0001-8098-9688

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNigella sativa seeds have been used for the treatment of ailments. Lepidium sativum is another spice used in the treatment of asthma, cough, and bleeding piles. Despite their significance, a comprehensive synthesis of their ethnobotanical uses in Ethiopia remains limited. Therefore, this study was designed to carry out an ethnobotanical investigation on L. sativum and N. sativa seeds.

methodsThe study was conducted in Debre Berhan, Chacha, and Sheno towns located in the North Shewa Zone of the Amhara Regional State, Ethiopia. Semistructured interviews were employed among 65 informants to obtain ethnobotanical data. Data were entered into EpiData Version 3.1, then exported to SPSS Version 26.0 for statistical analysis. Descriptive statistics, including frequencies and percentages, were used to summarize the data. Ethnobotanical indices, including informant consensus factor (ICF) and fidelity level (FL), were calculated using the standard formulas. Associations between categorical and patterns of medicinal seed use were assessed using the Pearson chi-square test. Statistical significance was considered at p value of < 0.05.

resultsA total of 65 individuals participated in the study. The majority of the respondents (93.8%) reported having used these seeds. Among those, 84.6% used both seeds in combination. ICF values ranged from 0.000 to 0.933 across six disease categories. The highest was recorded for digestive problems (ICF = 0.967) and general health (ICF = 0.958), with 31 and 25 use-reports, respectively. The ethnobotanical indices showed a significant preference for the combined use of L. sativum and N. sativa with a frequency of citation (FC) value of 55 and a use value (UV) of 0.846.

conclusionsIn this study, people use L. sativum and N. sativa seeds mostly for digestive problems and general health conditions. Future studies should investigate the phytochemical composition, mechanisms of action, toxicological effects, and clinical relevance of commonly used preparations of L. sativum and N. sativa.

Indexed as

Lepidium sativumNigella sativaPlant ExtractsSeedsAdultEthiopiaEthnobotanyFemaleHumansMaleMiddle AgedPhytotherapyYoung AdultPlant ExtractsEthiopiafrequency of citationinformant consensus factorLepidium sativumNigella sativa

Identifiers

PMID42861453
PMCPMC13655771

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.