Evidence map›Paper›PMID 42861412›Full record

ArticleiScience2026

Hepatic TMEM30A deficiency disrupts lipid metabolism and liver regeneration through PPARα-ATGL pathway.

Yilin Zhou, Xulin Gan, Jianv Cheng, Ke Ren, Yu Guo, Aixue Zhang, Yishan Jin, Zhongyuan Ge, Jialuo Wang, Zhenyu Ju and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yilin ZhouSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Xulin GanZhejiang Chinese Medical University, Hangzhou 310053, China.
Jianv ChengZhejiang Chinese Medical University, Hangzhou 310053, China.
Ke RenKey Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Institute of Translational Medicine, Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, China.
Yu GuoCollege of Medicine and Health Sciences, China Three Gorges University, Yichang 443002, China.
Aixue ZhangKey Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Institute of Translational Medicine, Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, China.
Yishan JinKey Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Institute of Translational Medicine, Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, China.
Zhongyuan GeKey Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Institute of Translational Medicine, Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, China.
Jialuo WangKey Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Institute of Translational Medicine, Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, China.
Zhenyu JuKey Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, College of Life Science and Technology, Jinan University, Guangzhou, China.
Liyun ShiKey Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Institute of Translational Medicine, Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, China.
Lingling ZhangDepartment of Hematology, Center for Metabolic Medicine, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu 322000, China.
Leiming LiuKey Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Institute of Translational Medicine, Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lipid accumulation at early phase during liver regeneration is necessary process, its functional role and regulatory mechanisms remain unclear. Here, we investigated the role of TMEM30A, a β-subunit of P4-ATPases, in hepatic lipid homeostasis and regeneration.

Indexed as

hepatic steatosislipid accumulationpartial hepatectomyTRASWy-14643

Identifiers

PMID42861412
PMCPMC13654571

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.