Evidence map›Paper›PMID 42861367›Full record

ArticleSynthetic and systems biotechnology2027

Systems metabolic engineering of a plasmid-free

Runze Zhao, Changgeng Li, Chaoye Xu, Zhichao Chen, Haibo Xiong, Zichen Yu, Tang'en Shi, Lanxiao Li, Meng Yuan, Ling Ma and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Runze ZhaoCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Changgeng LiCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Chaoye XuCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Zhichao ChenCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Haibo XiongCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Zichen YuCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Tang'en ShiCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Lanxiao LiCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Meng YuanCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Ling MaCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Siyu ZhaoCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.
Hongyu DengState Key Laboratory of Green Papermaking and Resource Recycling, Qilu University of Technology (Shandong Academy of Science), Jinan, 250353, PR China.
Qingyang XuCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytidine is an important precursor for nucleoside pharmaceuticals, but its fermentative production is constrained by competing degradation, poor selectivity of pyrimidine flux, insufficient precursor supply, and energy-redox imbalance. In this study, a plasmid-free

Indexed as

Channel engineeringCytidineDynamic regulationEscherichia coliMetabolic engineeringRespiratory chain engineering

Identifiers

PMID42861367
PMCPMC13654479

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.