Evidence map›Paper›PMID 42861352›Full record

ArticleiScience2026

Neutrophil swarm formation on large targets.

Christian Wine, Anna Apostolopoulou, Charles P Lin, Derin Sevenler, Michael K Mansour, Daniel Irimia

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christian WineCenter for Engineering in Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA.
Anna ApostolopoulouDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Charles P LinCenter for Systems Biology and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA.
Derin SevenlerCenter for Engineering in Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA.
Michael K MansourDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Daniel IrimiaCenter for Engineering in Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA.

Funding

INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
In vivo Monitoring of Neutrophil Function in Patients after Stem Cell TransplantR01AI176658 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Daniel Irimia, Charles P. Lin · 2023 to 2026
$3.2M
The role of spleen tyrosine kinase (syk) in neutrophil responses to pathogenic fungi.R01AI132638 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MANSOUR, MICHAEL K · 2018 to 2021
$1.6M
NIAID NIH HHS R01 AI132638NIAID NIH HHS R01 AI176658NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

Neutrophils are smaller in size than most fungal hyphae. Yet, neutrophils can engage in collective actions known as swarming, during which they cover the hyphae and block their growth. To understand how neutrophil swarms cover large targets efficiently, we employed particle image velocimetry (PIV). We found that the process is initiated at a small number of sites on the surface of a large target. Radiating from these initial sites, waves of intracellular Ca

Indexed as

invasive fungal infectionsmicrofluidicsneutrophilsparticle image velocimetryswarming

Identifiers

PMID42861352
PMCPMC13654541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.