ArticleInfectious diseases & clinical microbiology2026
Eleven-Year Trends in Antimicrobial Resistance and Isolation Rates per 1000 Patient-Days of Key Gram-Positive and Gram-Negative Bacteria in a Tertiary Care Hospital in Türkiye (2014-2024).
Article in Infectious diseases & clinical microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study examined 11-year trends in antimicrobial resistance and resistant organism isolation rates per 1000 patient-days among key Gram-positive and Gram-negative bacteria in a tertiary-care hospital in Türkiye. Materials and Methods: Microbiology data were obtained from the first isolate per patient per admission between January 2014 and December 2024. Organisms were identified using VITEK MS/matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS). Antimicrobial susceptibility testing was performed using VITEK 2 or BD Phoenix, with disk diffusion used for selected agents. Clinical and Laboratory Standards Institute (CLSI) breakpoints were applied until 2015, and European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints thereafter. Resistance rates (%) and resistant organism isolation rates per 1000 patient-days were calculated. Results: Conclusion: Antimicrobial resistance patterns exhibited divergent trends across bacterial species. Increasing resistance rates and resistant organism isolation rates were observed in Graphical Abstract: Graphical Abstract.
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