Evidence map›Paper›PMID 42861332›Full record

ArticleEULAR rheumatology open2026

The EULAR points to consider regarding the development of criteria for the assessment of the disease activity in adult-onset Still's disease.

Piero Ruscitti, Tanja Stamm, Valentin Ritschl, Stéphane Mitrovic, Charlotte Girard-Guyonvarc'h, Helene Alexanderson, Birgit Barten, Carina Bostrøm, Dorothea Fell, Marco Gattorno and 14 more

Abstract read
In one paragraph

Article in EULAR rheumatology open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Piero RuscittiDivision of Rheumatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Tanja StammInstitute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna, Vienna, Austria.
Valentin RitschlInstitute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna, Vienna, Austria.
Stéphane MitrovicSorbonne University-AP-HP, Pitié-Salpêtrière Hospital, Rheumatology Department, Paris, France.
Charlotte Girard-Guyonvarc'hDivision of Rheumatology, Department of Medicine, University Hospital of Geneva, Geneva, Switzerland.
Helene AlexandersonDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Birgit BartenEULAR Research Partner, EULAR PARE, Zurich, Switzerland.
Carina BostrømDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.
Dorothea FellDeutsche Rheuma-Liga Bundesverband e. V., Bonn, Germany.
Marco GattornoIRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattie Autoinfiammatorie, Genoa, Italy.
Francis GuilleminUniversité de Lorraine, Inserm, UMR 1319 INSPIIRE, Nancy, France.
Melanie KörnerEULAR Research Partner, EULAR PARE, Zurich, Switzerland.
Martin KruscheIII Department of Medicine, Division of Rheumatology and Systemic Inflammatory Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Javier LlorcaEpidemiology, CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Pierre QuartierUniversité Paris-Cité, Paris, France.
Angelo RavelliDipartimento di Neuroscienze, Riabilitazione, Oftalmologia, genetica e Scienze Materno-infantili (DINOGMI), Università degli Studi di Genova and Direzione Scientifica, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Nicolas RosineImmunoregulation Unit, Department of Immunology, Institut Pasteur, Université de Paris, Paris, France.
Maud WieczorekSwiss Centre of Expertise in Life Course Research LIVES, Lausanne and Geneva, Geneva, Switzerland.
Tanita-Christina WilhelmerEULAR Research Partner, EULAR PARE, Zurich, Switzerland.
Miguel Ángel Gonzalez-GayDivision of Rheumatology, IIS-Fundación Jiménez Díaz, Madrid, Spain.
Cem GabayDivision of Rheumatology, Department of Medicine, University Hospital of Geneva, Geneva, Switzerland.
Bruno FautrelSorbonne University-AP-HP, Pitié-Salpêtrière Hospital, Rheumatology Department, Paris, France.
Eugen FeistDepartment of Rheumatology, Helios Clinic, and Experimental Rheumatology of the Otto-von-Guericke University, Magdeburg, Germany.
Roberto GiacomelliFondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aims to formulate European Alliance of Associations for Rheumatology (EULAR) points to consider (PtCs) regarding the development of criteria for the assessment of the disease activity in adult-onset Still's disease (AOSD). Methods: The Task Force consisted of 23 members from 7 different European countries. A systematic literature review and a 3-round Delphi exercise involving European Experts were conducted to support the formulation of overarching principles and PtCs. Results: Based on retrieved evidence and Experts' opinions, results of Delphi Rounds, and discussions, 3 overarching principles and 11 PtCs were developed. The Task Force agreed on the importance of an appropriate definition for the disease activity in AOSD to be valid, reliable, and easily transferable in a clinical setting. The development of specific criteria for the assessment of disease activity should include a precise definition of the clinical features that could better describe the patient condition. A clear definition of disease activity would help clinicians to adjust therapy and to identify refractory patients. A validated assessment of the disease activity is important to establish specifically designed and powered studies for comprehensive management of patients with AOSD. A uniform and reproducible definition of remission may facilitate the inclusion of a new therapeutic target into daily practice and clinical trials. Conclusions: The EULAR PtCs were produced regarding the development of criteria for the assessment of the disease activity in AOSD, to provide the basis for a clinical tool to be readily, reliably, and easily applied in clinical settings in order to improve patient management.

Identifiers

PMID42861332
PMCPMC13654457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.