Evidence map›Paper›PMID 42861187›Full record

ArticleCureus2026

Benchmarking Drug Library Compliance and Alert Rates in Smart Infusion Pumps: A Multicenter Retrospective Study.

Ivens Souza, Mona Mourad, Samantha J Burton, Jaculin Cole, Caio Plopper, Sofia R Fernandez, Aftab Alam

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Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ivens SouzaMedical Affairs, Baxter Healthcare Corporation, Deerfield, USA.
Mona MouradMedical Affairs, Baxter Healthcare Corporation, Mississauga, CAN.
Samantha J BurtonMedical Affairs, Baxter Healthcare Corporation, Deerfield, USA.
Jaculin ColeMedical Affairs, Baxter Healthcare Corporation, Deerfield, USA.
Caio PlopperMedical Affairs, Baxter Healthcare Corporation, Deerfield, USA.
Sofia R FernandezMedical Affairs, Baxter Healthcare Corporation, Deerfield, USA.
Aftab AlamMedical Affairs, Baxter Healthcare Corporation, Deerfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSmart infusion pumps with dose error-reduction software (DERS) generate alerts to prevent infusion programming errors. However, high alert volumes may contribute to alert fatigue and impact workflow efficiency. Benchmarking continuous quality improvement (CQI) data across institutions may help identify opportunities to optimize drug library (DL) performance. This study evaluated the relationship between DL compliance and alert-related metrics using a benchmarking approach.

methodsA retrospective multicenter analysis of smart infusion pump data was conducted across 90 institutions (99 data pulls), including 13,749,759 infusions. Key metrics included DL compliance, alert rate, override rate, and alerts resulting in reprogramming ("good catches"). Facilities with DL compliance <95% and ≥95% were compared, and Spearman correlation analyses were performed to assess associations between DL compliance and alert-related outcomes.

resultsThe overall DL compliance rate was 95.9%. The mean alert rate was 33.3% (±12.20), and the overall override rate was 96.4%. On average, one good catch occurred for every 34.5 DERS infusions. Benchmarking across institutions showed no statistically significant differences in alert rates, override rates, or good catch rates between facilities with DL compliance ≥95% and those with <95%. Correlation analyses demonstrated only weak associations between DL compliance and alert rate, override rate, and good catch metrics.

conclusionsBenchmarking CQI data across institutions demonstrates that high DL compliance alone does not necessarily indicate optimized smart infusion pump performance. Incorporating alert and override metrics into CQI analyses may help reduce non-actionable alert burden and support safer, more efficient infusion workflows.

Indexed as

alert fatiguebenchmarkingclinical decision supportcontinuous quality improvementdose error reduction softwaredrug library compliancemedication safetysmart infusion pumps

Identifiers

PMID42861187
PMCPMC13654324

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.