ReviewCJC open2026
Optical Coherence Tomography Findings Following Intravascular Lithotripsy in Calcified Coronary Artery Disease: A Systematic Review and Meta-Analysis.
Review in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Intravascular lithotripsy (IVL) has emerged as a novel technology for modifying calcified coronary lesions, whereas optical coherence tomography (OCT) enables high-resolution assessment of calcium modification and procedural outcomes. However, the mechanistic and procedural effects of IVL assessed by OCT across studies remain incompletely characterized. Methods: A systematic review and meta-analysis was conducted according to PRISMA guidelines and registered in PROSPERO (CRD420261332946). PubMed/MEDLINE, Cochrane Library, and Epistemonikos were searched from inception through February 2026. Randomized controlled trials and observational studies with extractable quantitative OCT outcomes were included. The primary endpoint was OCT-detected calcium fracture. Secondary endpoints included multiple calcium fractures, minimum stent area (MSA), stent expansion, acute lumen gain, procedural success, and in-hospital major adverse cardiovascular events (MACEs). Random-effects meta-analyses were performed to estimate pooled proportions or mean values with 95% confidence intervals (CIs). Results: Thirty studies encompassing a total of 3030 patients were included. OCT-detected calcium fracture occurred in 68% (95% CI 56%-79%) of lesions, whereas multiple fractures were observed in 34% (95% CI 26%-41%). IVL-treated lesions achieved favorable procedural metrics, including a pooled final MSA of 6.45 (95% CI 6.07-6.82) mm Conclusions: Coronary IVL assessed by OCT is frequently associated with calcium fracture and favorable procedural outcomes with high procedural success and low early adverse events.
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