ArticleQuantitative imaging in medicine and surgery2026
Vessel wall MRI predictors of postprocedural new ischemic brain lesions after endovascular treatment for basilar artery stenosis.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Diffusion-weighted imaging (DWI)-detected new ischemic brain lesions (NIBL) are common complications after endovascular treatment (EVT) for basilar artery stenosis (BAS), directly impacting functional outcomes in patients. This study aimed to explore the association between vulnerable plaque markers identified by high-resolution magnetic resonance imaging (HR-MRI) and NIBL, and to clarify their predictive value for postprocedural ischemic events. Methods: A total of 373 patients with BAS who underwent EVT were retrospectively enrolled in this study. Patients were classified into DWI-positive (DWI+) and DWI-negative (DWI-) groups based on the presence of NIBL on DWI within 48 hours post-procedurally. Plaque burden, distribution, remodeling type, enhancement rate, and degree of stenosis were evaluated using HR-MRI. To determine independent predictors of NIBL post-procedurally, multivariable logistic regression was applied. Results: NIBL developed in 188 patients (50.4%), with a mean age of 61.76±7.83 years, including 84 males. The DWI+ group exhibited significantly higher rates of positive remodeling (PR) (51.1% Conclusions: HR-MRI-derived vulnerable plaque markers (PE and PR) are closely associated with the occurrence of NIBL following EVT for BAS, providing imaging-based evidence for risk stratification and treatment optimization.
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