ArticleCureus2026
Multiple Neurological Complications and Multidrug-Resistant Bacterial Infections During Prolonged Intensive Care for Undocumented Meningoencephalitis in Côte d'Ivoire: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute meningoencephalitis requiring intensive care may be complicated by severe neurological injury and nosocomial infections. Hydrocephalus is well recognized, whereas spinal cord ischemia, central diabetes insipidus, and flaccid tetraparesis are rarely reported. Their coexistence, together with successive infections involving multidrug-resistant organisms, presents substantial diagnostic and therapeutic challenges. A previously healthy 32-year-old man presented with neck and back pain following a road traffic accident, subsequently developing cerebellar signs, acute confusion, and meningeal signs without fever. Cerebrospinal fluid (CSF) analysis revealed neutrophilic pleocytosis, elevated protein, and marked hypoglycorrhachia. Microbiological investigations were negative, and no causative pathogen was identified. Empirical antimicrobial therapy was followed by normalization of the CSF leukocyte count by hospital day 6. Despite this initial response, the patient required mechanical ventilation and developed shunt-dependent tetraventricular hydrocephalus, probable central diabetes insipidus, imaging findings suggestive of thoracic spinal cord ischemia, and areflexic flaccid tetraparesis with diffuse axonal sensorimotor neuropathy. His prolonged intensive care course was further complicated by successive nosocomial infections involving multidrug-resistant bacteria. He died on hospital day 70 from septic shock associated with
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