Evidence map›Paper›PMID 42860590›Full record

ArticleGut microbes2026

Vagal sensing of altered gut microbiota links to externalizing behaviors.

Min Joung Lee, In Soo Kim, So-Hyun Ahn, Woosuk Chung, Yea Eun Kang, Sang Min Jeon, Jong Hun An, Chang Hee Pyo, Jaehyun Jeong, Young Eun Kim and 17 more

Abstract read
In one paragraph

Article in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Min Joung LeeDepartment of Biochemistry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.ORCID 0000-0002-0314-7839
In Soo KimDepartment of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
So-Hyun AhnDepartment of Psychiatry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Woosuk ChungDepartment of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Yea Eun KangSystem Network Inflammation Control Research Center, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Sang Min JeonDepartment of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea.ORCID 0000-0002-7576-414X
Jong Hun AnDepartment of Biochemistry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Chang Hee PyoDepartment of Biochemistry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Jaehyun JeongDepartment of Biochemistry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Young Eun KimDepartment of Biochemistry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Jiyeon YoonDepartment of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Kwang-Yeon ChoiDepartment of Psychiatry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Seong Eun LeeResearch Center for Endocrine and Metabolic Disease, Chungnam National University College of Medicine, Daejeon, Republic of Korea.ORCID 0000-0002-6793-6108
Hyun Seok KimDepartment of Bioinspired Science, Ewha Womans University, Seoul, Republic of Korea.
Sunjae LeeSchool of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea.
Samantha O'KeeffeDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA, USA.
Junyoung O ParkDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA, USA.
June-Young LeeDepartment of Biology and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Jin-Woo BaeDepartment of Biology and Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.ORCID 0000-0001-6433-5270
Da Eun KimCenter for Advanced Biomolecular Recognition, Korea Institute of Science and Technology, Seoul, Republic of Korea.
Hyunbeom LeeCenter for Advanced Biomolecular Recognition, Korea Institute of Science and Technology, Seoul, Republic of Korea.
Seok-Hwan KimDepartment of Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Woon-Hong YeoGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Min-Kyung YeoDepartment of Pathology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Eungseok OhDepartment of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Eun-Kyeong JoDepartment of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea.ORCID 0000-0002-9623-9037
Jun Young HeoDepartment of Biochemistry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.ORCID 0000-0002-0859-0063

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interoceptive brain responses triggered by intestinal microbiota influence mood-related behaviors such as anxiety and depression. Although genetic mutations can alter the gut microbiome, how alterations in the gut microbiome associated with host genetic variations relate to behavioral outcomes is not fully understood. We investigated how Sirtuin 3 (

Indexed as

Behavior, AnimalGastrointestinal MicrobiomeVagus NerveAmygdalaAnimalsMaleMiceMice, Inbred C57BLMice, KnockoutSolitary NucleusGut microbiotamood disordernucleus of the solitary tract: gut–brain axisvagus nerve

Identifiers

PMID42860590
PMCPMC13656818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.