ArticleEchocardiography (Mount Kisco, N.Y.)2026
Longitudinal Left Atrial Remodeling With Pharmacological Rhythm Versus Rate Control in Paroxysmal and Persistent Atrial Fibrillation.
Article in Echocardiography (Mount Kisco, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeEvidence regarding left atrial (LA) remodeling with pharmacological rhythm control remains limited, particularly in patients with atrial fibrillation (AF) outside heart-failure-specific populations.
methodsThis single-center retrospective cohort included 156 adults with paroxysmal or persistent AF receiving mutually exclusive pharmacological rate-control (n = 92) or rhythm-control (n = 64) therapy who underwent two transthoracic echocardiograms. LA remodeling was assessed using serial echocardiography, and clinical outcomes were evaluated after the second examination.
resultsAmong 74 patients with paired left atrial volume index (LAVI) measurements, LAVI increased from 39.9 to 50.3 mL/m
conclusionPharmacological rhythm control was associated with more favorable longitudinal LA remodeling than rate control, including among patients without heart failure, and was also associated with a lower hazard of subsequent all-cause mortality or stroke hospitalization.
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