ArticleCureus2026
Trimodal Therapy for Primary Squamous Cell Carcinoma of the Vagina: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary vaginal squamous cell carcinoma (SCC) is a rare clinical entity, with few prospective studies regarding its treatment available in the literature. We report a case of a 64-year-old female patient with a two-year history of vulvar itching, burning, and intermittent vulvar bleeding. She was diagnosed with stage III (T2, N1, M0) vaginal SCC. The patient subsequently received chemotherapy with cisplatin, external beam radiation therapy (EBRT), as well as high-dose-rate (HDR) cylinder brachytherapy. She achieved a complete clinical and radiographic response, with no evidence of disease on examination or post-treatment PET at six-month follow-up. This case highlights a multimodal treatment approach for advanced vaginal SCC and contributes to the limited body of literature guiding management of this rare malignancy.
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