Evidence map›Paper›PMID 42859761›Full record

ArticleGynecologic oncology reports2026

Apparent diffusion coefficient values on MRI as biomarkers for pre operative prediction of prognostic factors in endometrial cancer.

Ashika Padival, Bijal Manish Patel, Chetana D Parekh, Ruchi Arora, Hitesh Rajpura, Kedar Padhiyar

Abstract read
In one paragraph

Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ashika PadivalGynaecological Oncology, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India.
Bijal Manish PatelGynaecological Oncology, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India.
Chetana D ParekhGujarat Cancer and Research Institute, Ahmedabad, Gujarat, India.
Ruchi AroraGujarat Cancer and Research Institute, Ahmedabad, Gujarat, India.
Hitesh RajpuraRadiodiagnosis, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India.
Kedar PadhiyarRadiodiagnosis, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/objectives: Magnetic resonance imaging (MRI) is essential for preoperative assessment of endometrial carcinoma. Diffusion-weighted imaging (DWI)-derived apparent diffusion coefficient (ADC) values are being explored as quantitative, non-invasive biomarkers of tumor biology and aggressiveness. This study assessed the performance and interobserver reproducibility of ADC measurements for predicting prognostic factors. Methods: This study was conducted from June 2023 to June 2025 and included histologically confirmed endometrial carcinoma patients who underwent preoperative pelvic MRI. Patients with 3 T MRI outside the institute or unfit for primary surgery were excluded. Two radiologists independently measured focused-region and whole-lesion ADC values. Interobserver agreement was assessed using paired Results: Fifty-one patients were included, with endometrioid adenocarcinoma being the predominant histological subtype (92.2%). The mean ADC was 747.13 × 10 Conclusion: Focused ROI-based ADC assessment is practical, reproducible, contrast-free, and may improve risk stratification, surgical planning, and individualized management, especially where molecular testing is limited.

Indexed as

Apparent diffusion coefficientDiffusion-weighted imagingEndometrial carcinomaGynecologic oncologyMRIPrognostic biomarkers

Identifiers

PMID42859761
PMCPMC13653426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.