Evidence map›Paper›PMID 42859721›Full record

ReviewReviews in cardiovascular medicine2026

The Role of Autoimmune Diseases in the Development of Aortic Aneurysms.

Jaroslav Michalek, Martin Petrek, Jana Petrkova

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jaroslav MichalekDepartment of Clinical and Molecular Pathology, University Hospital Olomouc, 77900 Olomouc, Czech Republic.ORCID https://orcid.org/0000-0002-3454-5880
Martin PetrekDepartment of Pathological Physiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, 77900 Olomouc, Czech Republic.ORCID https://orcid.org/0000-0002-4517-7825
Jana PetrkovaDepartment of Pathological Physiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, 77900 Olomouc, Czech Republic.ORCID https://orcid.org/0000-0003-4581-3809

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic aneurysms are abnormal dilations of the aortic wall and represent a significant cause of morbidity and mortality worldwide. In many cases, especially when the thoracic aorta is involved, the first and only symptom is sudden death. While aortic aneurysms are traditionally associated with factors such as advanced age, hypertension, and atherosclerosis, growing evidence points to a critical role for autoimmune diseases in their pathogenesis. The hallmarks of autoimmune disorders, such as chronic systemic inflammation, immune dysregulation, and vascular tissue remodeling, can create a pro-aneurysmal environment within the vasculature. This review explores the complex interplay between autoimmune diseases and aortic aneurysm formation, focusing on pathogenic mechanisms, specific disease associations, and implications for diagnosis and management. A better understanding of these relationships is vital for advancing therapeutic strategies aimed at mitigating vascular complications in affected patients.

Indexed as

aortic aneurysmautoimmune diseasesdiagnosisrisk factorssudden cardiac deaththerapeutics

Identifiers

PMID42859721
PMCPMC13653162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.