ArticleReviews in cardiovascular medicine2026
Risk of Atrial Fibrillation Recurrence After Modified Cox-Maze IV Surgery: Comparing Atrial Functional Mitral Regurgitation and Rheumatic Mitral Regurgitation.
Article in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Background: The comparative efficacy of the modified Cox-Maze IV procedure (CMP IV) in treating atrial fibrillation (AF) in patients with atrial functional mitral regurgitation (AFMR) and those with rheumatic mitral regurgitation (RMR) remains inadequately characterized. Therefore, this study aimed to evaluate and compare postoperative AF recurrence rates and clinical outcomes between these two etiologically distinct groups. Methods: A retrospective analysis was conducted on 221 patients (AFMR group: n = 53; RMR group: n = 168) with concomitant long-standing persistent AF who underwent mitral valve surgery combined with modified CMP IV or other concomitant procedures at our institution between January 2019 and September 2024. To address baseline imbalances, propensity score matching was performed at a 1:1 ratio, resulting in well-matched cohorts of 32 patients with AFMR and 32 with RMR patients for the final analysis. The primary endpoint was AF recurrence. Statistical comparisons utilized chi-square tests, Results: After PSM, 32 patients remained in each group with balanced baselines. The AFMR group showed a higher trend toward postoperative AF recurrence. Pre‑discharge AF recurrence rates did not differ significantly between groups (37.5% vs. 12.5%; Conclusions: In patients undergoing mitral valve surgery with modified CMP IV, those with AFMR exhibit a significantly higher risk of postoperative AF recurrence compared with patients with RMR, despite similar early-term survival outcomes. Postoperative AF monitoring should be intensified in patients with AFMR to improve long-term outcomes.
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