ReviewCureus2026
Orthopedic Risks and Recovery Considerations in Long COVID: A Narrative Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The COVID-19 pandemic left a lasting imprint on orthopedic surgery, initially through widespread reductions in care delivery and subsequently through the complex challenges posed by Long COVID syndrome. Emerging literature describes Long COVID-related alterations in bone mineral density, delayed wound healing, prolonged inflammation, persistent chronic pain, and increased perioperative risks. Long COVID may adversely affect skeletal integrity through inflammatory, hypoxic, and angiotensin-converting enzyme 2-mediated pathways, potentially leading to bone loss and increased fracture susceptibility. Persistent inflammation, endothelial dysfunction, thrombotic tendency, and neurocognitive impairment may also increase perioperative vulnerability, while chronic musculoskeletal pain, reduced exercise capacity, and post-exertional malaise may complicate rehabilitation and functional recovery. Although orthopedic-specific evidence remains limited, the available findings suggest that Long COVID may represent an underrecognized risk modifier relevant to surgical planning and postoperative management. Greater awareness of these mechanisms may improve patient counseling, risk stratification, and rehabilitation strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.