Evidence map›Paper›PMID 42859641›Full record

ArticleInfection and drug resistance2026

Clinical and Economic Outcomes Associated with Rapid Antimicrobial Susceptibility Reporting and Dual-Card Testing in ICU Bloodstream Infections.

Ya Xu, Yue Feng, Chunlei Shi, Panpan Ma, Xiu Cai, Ling Huang, Xinyu Liu, Keke Shao, Linlin Xu

Abstract read
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Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ya XuDepartment of Laboratory Medicine, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu province, People's Republic of China.
Yue FengDepartment of Laboratory Medicine, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu province, People's Republic of China.
Chunlei ShiDepartment of Laboratory Medicine, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu province, People's Republic of China.
Panpan MaDepartment of Laboratory Medicine, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu province, People's Republic of China.
Xiu CaiDepartment of Laboratory Medicine, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu province, People's Republic of China.
Ling HuangDepartment of Laboratory Medicine, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu province, People's Republic of China.
Xinyu LiuDepartment of Laboratory Medicine, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu province, People's Republic of China.
Keke ShaoDepartment of Laboratory Medicine, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu province, People's Republic of China.
Linlin XuDepartment of Laboratory Medicine, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu province, People's Republic of China.ORCID 0009-0001-0100-1692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the clinical and economic outcomes associated with implementation of an optimized blood culture workflow in intensive care unit (ICU) patients with bloodstream infections. Patients and Methods: From March 2022 to June 2023, the laboratory implemented a multi-modal workflow optimization including satellite blood culture incubation in the emergency department, upgraded blood culture bottles, rapid MALDI-TOF MS identification, automated rapid antimicrobial susceptibility testing (AST) reporting, and dual AST cards for Gram-negative bacteria. The pre-optimization group included 107 adult ICU patients with positive blood cultures (March 2021 - February 2022). The post-optimization group included 153 patients (September 2023 - August 2024). Results: Compared to the final AST report in the pre-optimization group, the rapid AST report in the post-optimization group was 19.6 hours faster ( Conclusion: This multimodal workflow optimization for ICU patients with BSIs, incorporating automated rapid AST reporting and dual-AST-card-enabled expanded antimicrobial panels, shortened laboratory turnaround time. It was associated with earlier opportunities for targeted antimicrobial therapy and suggests potential clinical-economic benefits, alongside possible mitigation of antimicrobial-resistance risk.

Indexed as

antimicrobial stewardshipblood culturehealth economicsworkflow optimization

Identifiers

PMID42859641
PMCPMC13653512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.