Evidence map›Paper›PMID 42859540›Full record

ArticleAIMS microbiology2026

The stone-degrading metabolic potential of the urinary microbiome: Sexual dimorphism and dysbiosis in urolithiasis.

Ying Li, Chengqiang Mo, Yun Xie, Zhixin Huang, Lingwu Chen, Xinqiang Xie, Junhang Luo, Shixuan Huang, Shuangjian Jiang, Tianhao Zhang and 3 more

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Article in AIMS microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Ying LiState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Key Laboratory of Big Data Technologies for Food Microbiological Safety, State Administration for Market Regulation, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, China.
Chengqiang MoDepartment of Urology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.
Yun XieDepartment of Urology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.
Zhixin HuangDivision of Gastrointestinal Surgery Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.
Lingwu ChenDepartment of Urology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.
Xinqiang XieState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Key Laboratory of Big Data Technologies for Food Microbiological Safety, State Administration for Market Regulation, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, China.
Junhang LuoDepartment of Urology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.
Shixuan HuangState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Key Laboratory of Big Data Technologies for Food Microbiological Safety, State Administration for Market Regulation, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, China.
Shuangjian JiangDepartment of Urology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.
Tianhao ZhangDivision of Gastrointestinal Surgery Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.
Jumei ZhangState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Key Laboratory of Big Data Technologies for Food Microbiological Safety, State Administration for Market Regulation, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, China.
Rongpei WuDepartment of Urology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.
Qingping WuState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food, Key Laboratory of Big Data Technologies for Food Microbiological Safety, State Administration for Market Regulation, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urolithiasis is a prevalent global health burden characterized by high recurrence rates and marked sexual dimorphism. While the gut microbiome's role in oxalate degradation is established, the functional capacity of the local urinary microbiome remains largely unexplored. This study investigated the composition and function of the urinary microbiome in 40 healthy volunteers and 61 urolithiasis patients using 16S rRNA amplicon sequencing, alongside a retrospective analysis of stone composition in 2027 patients. We identified a diverse, ecologically structured microbiome in healthy urine dominated by genera such as

Indexed as

Lactobacillussex discrepancyurinary microbiomeurolith degradationurolithiasis

Identifiers

PMID42859540
PMCPMC13652743

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.