Evidence map›Paper›PMID 42859525›Full record

ReviewReviews in cardiovascular medicine2026

Fibroblast Activation Protein Inhibitor Positron Emission Tomography Imaging in Atrial Fibrillation: Current Evidence and Future Perspectives.

Yi Xu, Huiyi Qiu, Chuxian Guo, Qianyun Wang, Yongjin Tang, Chongyi Huang, Jun Guo, Feifei Wang

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi XuSchool of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0003-4449-5589
Huiyi QiuSchool of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China.
Chuxian GuoSchool of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China.
Qianyun WangHealth Management Division, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), 528308 Foshan, Guangdong, China.
Yongjin TangSchool of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China.
Chongyi HuangSchool of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China.
Jun GuoSchool of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0003-9865-2196
Feifei WangSchool of The First Clinical Medical, University of Jinan, 510632 Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast activation protein inhibitor (FAPI) positron emission tomography/computed tomography (PET/CT) has emerged as a promising molecular imaging modality for visualizing fibroblast activation and extracellular matrix remodeling. In addition to its established role in oncology imaging, FAPI PET/CT is gaining recognition in the evaluation of cardiovascular disease. Emerging evidence suggests that this technique may provide molecular insights into atrial fibroblast activation and the development of a fibrotic substrate in atrial fibrillation. Meanwhile, related findings from other arrhythmias further support a potential link between myocardial fibroblast activation and electrophysiological remodeling. This review summarizes the current evidence on FAPI PET/CT imaging in atrial fibrillation, discusses related findings in other cardiovascular conditions, and highlights future directions for research in arrhythmia imaging.

Indexed as

arrhythmiaatrial fibrillationfibroblast activation protein inhibitormyocardial fibrosispositron emission tomography

Identifiers

PMID42859525
PMCPMC13653197

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.