Evidence map›Paper›PMID 42859521›Full record

ArticleReviews in cardiovascular medicine2026

The "Floating Lotus" Sign on Intracardiac Echocardiography: Characterization and Predictors of a Novel Left Atrial Appendage Pseudo-Thrombus.

Liang Zhang, Yanyan Bai, Yanhua Zhu, Jianhua Sun, Liuliu Feng, Jingyu Zhang, Songqun Huang

Abstract read
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Article in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Liang ZhangDepartment of Cardiology, Third Affiliated Hospital of Naval Medical University, 200438 Shanghai, China.ORCID https://orcid.org/0000-0002-7163-0021
Yanyan BaiDepartment of Cardiology, Shidong Hospital, 200438 Shanghai, China.
Yanhua ZhuDepartment of Cardiology, Third Affiliated Hospital of Naval Medical University, 200438 Shanghai, China.
Jianhua SunDepartment of Cardiology, Shidong Hospital, 200438 Shanghai, China.
Liuliu FengDepartment of Cardiology, Shidong Hospital, 200438 Shanghai, China.
Jingyu ZhangDepartment of Cardiology, Third Affiliated Hospital of Naval Medical University, 200438 Shanghai, China.
Songqun HuangDepartment of Cardiology, Changhai Hospital, Naval Medical University, 200433 Shanghai, China.ORCID https://orcid.org/0000-0001-9975-3683

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intracardiac echocardiography (ICE) is increasingly used for left atrial appendage (LAA) assessment during atrial fibrillation (AF) procedures. We describe a novel, thrombus-mimicking artifact on ICE, termed the "Floating Lotus" sign. Methods: In this retrospective multicenter study, we analyzed data from 172 patients undergoing ICE-guided AF ablation and/or LAA occlusion. The incidence, imaging features, and clinical correlates of the "Floating Lotus" sign were assessed. Results: The "Floating Lotus" sign was observed in 48 patients (27.9%). It manifested as a mobile, echogenic mass within an anechoic space, revealing an underlying pericardial effusion. Patients exhibiting the sign had a higher prevalence of recent stroke (35.4% vs. 15.3%, Conclusion: The "Floating Lotus" sign is a common ICE pseudo-thrombus, often associated with heart failure. Accurate recognition of this sign, based on its dynamic imaging features, is therefore critical to prevent misdiagnosis and avoid unnecessary procedural cancellation or anticoagulation changes.

Indexed as

atrial fibrillationcatheter rotation maneuverintracardiac echocardiographyleft atrial appendagepseudo-thrombus

Identifiers

PMID42859521
PMCPMC13653155

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.