ArticleJournal of arrhythmia2026
Sleep-Disordered Breathing and Sleep Fragmentation in Relation to Atrial Fibrillation Risk: A Systematic Review and Meta-Analysis.
Article in Journal of arrhythmia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Atrial fibrillation (AF) is one of the most prevalent cardiac arrhythmias worldwide. This study aimed to evaluate the association between sleep-disordered breathing (SDB), primarily assessed using the apnea-hypopnea index (AHI), and AF risk, with additional analysis of sleep fragmentation parameters such as wake after sleep onset (WASO) and arousal index (AI). Methods: This systematic review and meta-analysis followed Cochrane Handbook recommendations and PRISMA guidelines, with protocol registration in PROSPERO (No. 127490). Randomized controlled trials (RCTs) and observational cohort studies assessing sleep disturbances and AF were included. MEDLINE, Cochrane Library, and Scopus were searched from inception to February 2026. Extracted data included study characteristics, demographics, cardiovascular risk factors, and sleep metrics. Outcomes were incident and recurrent AF. A random-effects model was applied. Results: Twenty-one cohort studies (611,898 participants) were included. SDB was associated with increased incident AF risk (RR 1.67, 95% CI 1.41-1.97; Conclusion: Sleep disturbances are significantly associated with both incident and recurrent AF and may represent modifiable risk factors.
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Registered trials
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