Evidence map›Paper›PMID 42859486›Full record

ReviewMaedica2026

Robotic Versus Laparoscopic Hepatectomy: a Systematic Review of Perioperative and Short-Term Oncologic Outcomes.

Silvana Leanza, Danilo Coco

Abstract readReview
In one paragraph

Review in Maedica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Silvana LeanzaDepartment of General, Robotic and Oncologic Surgery, Giglio Foundation Hospital, Cefalù, Palermo, Italy.
Danilo CocoDepartment of General, Robotic and Oncologic Surgery, Giglio Foundation Hospital, Cefalù, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Minimally invasive liver surgery (MILS) has progressively evolved from minor resections to technically demanding major hepatectomies. While laparoscopic hepatectomy is now widely established, robotic platforms have emerged as a promising alternative, potentially overcoming the ergonomic and technical limitations of conventional laparoscopy. This umbrella review synthesizes current comparative evidence to inform surgical decision-making. Methods: An umbrella review of the literature was conducted in accordance with PRISMA guidelines. Systematic reviews, meta-analyses, and network meta-analyses evaluating robotic versus laparoscopic hepatectomy were identified through searches of PubMed, Embase and the Cochrane Library (2020-2025). Primary outcomes included operative time, estimated blood loss and conversion to open surgery. Secondary outcomes included postoperative morbidity, length of hospital stay and R0 resection rate. Data overlap across included secondary analyses was explicitly acknowledged; pooled estimates cited in this review are derived from the most comprehensive single source identified for each metric and are referenced accordingly. Studies including benign pathologies were noted, and oncologic metrics are reported separately for malignant subgroups where data permitted. Results: Nine high-quality systematic reviews and meta-analyses - including two network meta-analyses - published between 2020 and 2025 were included in this umbrella review. These secondary analyses draw upon overlapping pools of primary retrospective cohort studies, likely capturing a large but not fully independent population of patients. Robotic hepatectomy was consistently associated with significantly lower estimated blood loss (WMD -110 mL; 95% CI -142 to -78; p < 0.001) and reduced conversion to open surgery (OR 0.63; 95% CI 0.50-0.79; p < 0.001) compared with laparoscopy. Operative time was longer for robotic surgery (WMD +42 min; 95% CI +28 to +56; p < 0.001), although this difference attenuated after the learning curve. Overall morbidity and length of hospital stay were comparable. R0 resection rates were equivalent (>90% in both groups). Lymph node yield was significantly higher in robotic surgery among malignant cases (+1.1 nodes; 95% CI 0.3-1.9; p = 0.01). Conclusions: Both robotic and laparoscopic hepatectomy are safe and effective minimally invasive techniques. Robotic surgery provides measurable perioperative advantages in blood loss control and conversion rates, particularly in complex resections. A statistically significant improvement in lymph node yield favoring robotic surgery was identified in oncologic cases and warrants further investigation. Long-term oncologic equivalence remains to be confirmed by prospective data.

Indexed as

hepatectomylaparoscopic surgeryliver resectionmajor hepatectomyminimally invasive surgeryrobotic surgeryumbrella review

Identifiers

PMID42859486
PMCPMC13650645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.