ReviewArhiv za higijenu rada i toksikologiju2026
Antimicrobial stewardship challenges during the COVID-19 pandemic: implications of antibiotic overuse and antimicrobial resistance.
Review in Arhiv za higijenu rada i toksikologiju, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
2 authors.
Funding
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Abstract
The coronavirus disease 2019 (COVID-19) pandemic significantly influenced antimicrobial prescribing practices worldwide, raising concerns about antimicrobial resistance (AMR). This narrative review assesses the relationship between COVID-19 and antibiotic use, focusing on bacterial co-infections, prescribing patterns, long-term implications for AMR, and the role of multidisciplinary antimicrobial and diagnostic stewardship, preventive strategies, and the One Health approach in reducing disproportionate antibiotic exposure. To this end we ran a subject search across PubMed/MEDLINE, Scopus, Web of Science, the Cochrane Database of Systematic Reviews, Ovid, and Google Scholar for studies selected according to predefined inclusion and exclusion criteria. Despite relatively low rates of confirmed bacterial co-infections, antibiotic use remained disproportionately high, particularly during the early stages of the pandemic, highlighting challenges in clinical decision-making under diagnostic uncertainty. Excessive and inappropriate antibiotic prescribing may have contributed to the global AMR burden. Strengthening antimicrobial stewardship programmes, improving diagnostic accuracy and promoting evidence-based prescribing are therefore essential. Multidisciplinary antimicrobial stewardship interventions, rapid molecular diagnostics and vaccination-associated reductions in antibiotic prescribing emerge as complementary strategies for limiting unnecessary antimicrobial exposure, while the environmental consequences of antibiotic use further emphasise the relevance of the One Health approach. Continued surveillance and research are needed to better understand the long-term impact of the pandemic on AMR.
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Registered trials
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