ArticleIndian journal of pediatrics2026
The Role of Point-of-Care Lung Ultrasound in Diagnosing Ventilator-Associated Pneumonia in Pediatric Patients.
Article in Indian journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThis study aimed to assess the diagnostic accuracy of LUS for diagnosing VAP and to develop a new score based on Clinical Pulmonary Infection Score (CPIS) incorporating LUS to assess its accuracy for pediatric VAP diagnosis.
methodsA prospective observational study was conducted over one year (Nov 2022-Nov 2023) in the PICU of a tertiary care hospital in North India. A total of 112 mechanically ventilated children, aged 1-12 y with new respiratory deterioration and CPIS > 6 were enrolled. LUS, CXR, and endotracheal aspirate cultures were performed. LUS characteristics were analysed, and a composite score, the Lung Ultrasound Pulmonary Assessment Score (LUPAS), was developed.
resultsAmong 94 culture-confirmed VAP cases, LUS demonstrated high diagnostic performance. Coalescent B-lines (55.3%) and subpleural consolidations with air bronchograms (17%) had sensitivities and specificities of 75%/90% and 70%/95%, respectively. Integration of LUS into CPIS improved diagnostic accuracy, with the combined score yielding 90% sensitivity and 95% specificity, PPV of 85% and NPV of 95%, AUC 0.925.
conclusionsLUS appears to be a promising adjunctive imaging modality for evaluating VAP in mechanically ventilated paediatric patients.
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