Evidence map›Paper›PMID 42859214›Full record

ArticleEuropean journal of clinical nutrition2026

Prevalence and impact of sarcopenic obesity at hospital admission according to ESPEN-EASO approach on functional status of older adults: results of a retrospective and prospective observational study.

Gianluca Gortan Cappellari, Rocco Barazzoni, Nicola Veronese, Paolo De Colle, Giuseppe Castiglia, Matteo Bianchini, Carlo Cortese, Sabrina Rampazzo, Anna Rizza, Giovanni Zampieri and 1 more

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Article in European journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

11 authors.

Gianluca Gortan CappellariDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Rocco BarazzoniDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Nicola VeroneseSaint Camillus International University of Health Sciences, Faculty of Medicine, Rome, Italy.
Paolo De ColleUCO Geriatria, ASUGI, Trieste, Italy.
Giuseppe CastigliaUCO Geriatria, ASUGI, Trieste, Italy.
Matteo BianchiniDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Carlo CorteseDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Sabrina RampazzoDietetics School, University of Trieste, Pordenone Campus, Pordenone, Italy.
Anna RizzaDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Giovanni ZampieriDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Michela ZanettiDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy. zanetti@units.it.ORCID http://orcid.org/0000-0002-2634-6363

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesSarcopenic obesity (SO) is associated with adverse outcomes. This study aimed to assess the prevalence of SO diagnosed using the ESPEN-EASO approach and its correlations with functional impairment in an acute geriatric setting. SUBJECTS/

methodsObservational study including 453 older adults admitted to a Geriatric Unit. According to the ESPEN-EASO approach, patients were screened for obesity (BMI), assessed for handgrip strength (HGS, dynamometry), and body composition (bioimpedance analysis). SO was defined by low HGS, reduced relative to body weight skeletal muscle mass (SMM%), and increased relative fat mass (FM%). Screen-positive patients not meeting SO criteria were classified as obese (OB). Screen-negative patients with low SMM% and HGS were defined as sarcopenic (SARC); the remaining served as control (NS-NO). Functional status was investigated by IADL and by basal ADL collected at admission, during hospitalization, and at discharge and analyzed using trajectory modeling and univariate and multivariate adjusted models.

resultsAmong enrolled patients (mean age: 84.9 ± 7.0 y, F: 236, 52.1%), 36 (7.9%) had SO, 65 (14.3%) OB, 98 (21.0%) SARC, and 254 (56.7%) NS-NO. In multivariate analyses (NS-NO as reference) only SO demonstrated an increased risk of impaired ADL at discharge while OB and SARC did not. Trajectory modeling confirmed an SO-specific association with functional impairment followed by lower ADL recovery. Age, malnutrition, and cognitive impairment were independently associated with reduced ADL at admission and at discharge and with IADL.

conclusionsSarcopenic obesity is associated with a higher risk of poor ADL at discharge, emphasizing the importance of personalized obesity phenotyping in hospitalized older adults.

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PMID42859214

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