Evidence map›Paper›PMID 42859144›Full record

ArticleJournal of translational medicine2026

Impact of methylation and mutation modifications on melanoma progression through evaluation of paired primary and secondary lesions from same patients.

Antonella Manca, Maria Cristina Sini, Luca Nuvoli, Sara Simi, Silvia Costabile, Guido Bellezza, Vincenzo De Giorgi, Antonio Guadagno, Paola Ghiorzo, Mario Mandalà and 3 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Antonella MancaInstitute of Genetic & Biomedical Research (IRGB), Unit of Cancer Genetics, National Research Council (CNR), Sassari, 07100, Italy.
Maria Cristina SiniInstitute of Genetic & Biomedical Research (IRGB), Unit of Cancer Genetics, National Research Council (CNR), Sassari, 07100, Italy.
Luca NuvoliInstitute of Genetic & Biomedical Research (IRGB), Unit of Cancer Genetics, National Research Council (CNR), Sassari, 07100, Italy.
Sara SimiSection of Pathology, Department of Health Sciences, University of Florence, Florence, Italy.
Silvia CostabileUnit of Medical Oncology, Department of Medicine & Surgery, University of Perugia, Perugia, Italy.
Guido BellezzaSection of Pathology, Department of Medicine & Surgery, University of Perugia, Perugia, Italy.
Vincenzo De GiorgiSection of Dermatology, Department of Health Sciences, University of Florence, Florence, Italy.
Antonio GuadagnoU.O. Anatomia Patologica Ospedaliera, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Paola GhiorzoCancer Genetics, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Mario MandalàUnit of Medical Oncology, Department of Medicine & Surgery, University of Perugia, Perugia, Italy.
Daniela MassiSection of Pathology, Department of Health Sciences, University of Florence, Florence, Italy.
Giuseppe PalmieriInstitute of Genetic & Biomedical Research (IRGB), Unit of Cancer Genetics, National Research Council (CNR), Sassari, 07100, Italy. gpalmieri@yahoo.com.ORCID http://orcid.org/0000-0002-4350-2276
Epigenetic Immune-Oncology Consortium AIRC (EPICA)

Funding

Associazione Italiana per la Ricerca sul Cancro "Programma di ricerca 5 per Mille 2018-Id. 21073"
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cutaneous melanomaMelanoma pathogenesisMethylation profilingMutational statusPrognosis

Identifiers

PMID42859144
PMCPMC13654216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.