In one paragraphArticle in CNS neuroscience & therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Heyu ZhangDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.ORCID https://orcid.org/0000-0001-9700-6975 Ningning WangDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.ORCID https://orcid.org/0009-0002-4414-6282 Jingjing ChenDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.ORCID https://orcid.org/0009-0002-3931-2055 Jinming ZhangDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.
Yicong LiuDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.ORCID https://orcid.org/0009-0009-1745-9321 Yuting LuoDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.
Yingting LuoDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.
Ziheng WeiDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.
Kailin WuDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.
Ziyi ChenDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.ORCID https://orcid.org/0000-0001-6790-1258 Guanzhong NiDepartment of Neurology, The First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.ORCID https://orcid.org/0000-0002-2334-3423 Funding
Guangdong Province International Cooperation Base for Early Intervention and Functional Rehabilitation of Neurological Diseases 2020A0505020004Guangdong Provincial Clinical Research Center for Neurological Diseases 2020B1111170002Guangdong Provincial Engineering Center for Major Neurological Disease TreatmentGuangdong Provincial Translational Medicine Innovation Platform for Diagnosis and Treatment of Major Neurological DiseaseGuangzhou Clinical Research and Translational Center for Major Neurological DiseasesNational Key Research and Development Program of China 2022YFC2503804National Natural Science Foundation of China 81801287National Natural Science Foundation of China 81971203National Natural Science Foundation of China 82001234National Natural Science Foundation of China 82271489Science and Technology Program of Guangzhou, China 2024A04J4564
6 · The paper itselfAbstract
purposeNeuroinflammation is a key pathogenic mechanism in temporal lobe epilepsy, quantifiable in vivo using positron emission tomography targeting the translocator protein. This study integrated [
methodsA prospective study of 24 TLE patients and 24 healthy controls (HCs) was conducted. PET/MRI data were available for 24 TLE patients and 7 HCs, while cytokine data were available for all 24 participants in both groups. Standardized uptake value ratios of [
resultsCompared with HCs, TLE patients demonstrated significantly increased [
conclusion[
Indexed as
CytokinesEpilepsy, Temporal LobeNeuroinflammatory DiseasesAdultFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPositron-Emission TomographyProspective StudiesPyrazolesPyrimidinesYoung AdultCytokinesN,N-diethyl-2-(2-(4-(2-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo(1,5-a)pyrimidin-3-yl)acetamidePyrazolesPyrimidinesneuroinflammationPET/MRIserum cytokinestemporal lobe epilepsytranslocator protein
Identifiers
PMID42857895
PMCPMC13653323
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