ArticleVirus evolution2026
A divergent hepatitis A virus lineage in wild western lowland gorillas and central chimpanzees supports localized circulation and expands HAV diversity.
Charles Sanctorum, Matheus A C Cosentino, Amandine Esteban, Christelle Butel, Innocent Ndong Bass, Simon-Pierre Ndimbo-Kumugo, Steve Ahuka-Mundeke, Eric Leroy, Charles Kouanfack, Ahidjo Ayouba and 1 more
Abstract read
In one paragraphArticle in Virus evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Charles SanctorumRecherches Translationnelles sur le VIH et les Maladies Infectieuses (TransVIHMI), University of Montpellier, Institut National de la Santé et de la Recherche Médicale, Institut de Recherche Pour le Développement, 911 Avenue Agropolis, 34394 Montpellier, France.ORCID https://orcid.org/0009-0008-1168-1469 Matheus A C CosentinoLaboratório de Diversidade e Doenças Virais, Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rua Professor Rodolpho Paulo Rocco, s/n, Cidade Universitária, Rio de Janeiro, RJ 21941-617, Brazil.
Amandine EstebanRecherches Translationnelles sur le VIH et les Maladies Infectieuses (TransVIHMI), University of Montpellier, Institut National de la Santé et de la Recherche Médicale, Institut de Recherche Pour le Développement, 911 Avenue Agropolis, 34394 Montpellier, France.
Christelle ButelRecherches Translationnelles sur le VIH et les Maladies Infectieuses (TransVIHMI), University of Montpellier, Institut National de la Santé et de la Recherche Médicale, Institut de Recherche Pour le Développement, 911 Avenue Agropolis, 34394 Montpellier, France.
Innocent Ndong BassCentre de Recherche sur les Maladies Emergentes et Réémergentes (CREMER), Virology Laboratory IMPM-IRD, Rue Elig-Essono, Yaoundé, P.O. Box 1857, Cameroon.
Simon-Pierre Ndimbo-KumugoNational Institute of Biomedical Research, Virology Department, Avenue de la Démocratie, BP 1197 Kinshasa, Democratic Republic of the Congo.
Eric LeroyRecherches Translationnelles sur le VIH et les Maladies Infectieuses (TransVIHMI), University of Montpellier, Institut National de la Santé et de la Recherche Médicale, Institut de Recherche Pour le Développement, 911 Avenue Agropolis, 34394 Montpellier, France.ORCID https://orcid.org/0000-0003-0022-0890 Ahidjo AyoubaRecherches Translationnelles sur le VIH et les Maladies Infectieuses (TransVIHMI), University of Montpellier, Institut National de la Santé et de la Recherche Médicale, Institut de Recherche Pour le Développement, 911 Avenue Agropolis, 34394 Montpellier, France.ORCID https://orcid.org/0000-0002-5081-1632 Martine PeetersRecherches Translationnelles sur le VIH et les Maladies Infectieuses (TransVIHMI), University of Montpellier, Institut National de la Santé et de la Recherche Médicale, Institut de Recherche Pour le Développement, 911 Avenue Agropolis, 34394 Montpellier, France.ORCID https://orcid.org/0000-0001-6738-8730 Funding
Natural SIV Reservoirs and Human Zoonotic RiskR01AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2001 to 2022
$6.1MNIAID NIH HHS R01 AI050529
6 · The paper itselfAbstract
Hepatitis A virus (HAV) is a ubiquitous human pathogen that may cause acute liver disease. Despite the availability of effective vaccines, high prevalence rates are still reported in Southeast Asia and Africa, where sanitation conditions are poor. Although seven genotypes are known, including three in humans, three in non-human primates (NHP), and one recently identified in alpacas, the diversity, ecology, and evolutionary history of HAV remain poorly understood. In a pilot study of virome molecular characterization of wild African apes by using oligonucleotide probes enrichment, HAV sequences were detected in two animals (2/105; 1.9%): one from a western lowland gorilla (
Indexed as
apesCentral Africaevolutionfaeceshepatitis Azoonosis
Identifiers
PMID42857880
PMCPMC13652649
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