ArticleACS organic & inorganic Au2026
Substituent-Controlled Double Orthometalation and Anticancer Activity in Half-Sandwich Ir(III) Complexes Bearing C
Article in ACS organic & inorganic Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Platinum-based chemotherapeutic agents remain among the most widely used anticancer drugs; however, they show two main limitations: intrinsic or acquired resistance and severe side effects. To address these limitations, the design of alternative metal-based complexes with tunable properties is of growing interest. In this work, we report the rational design and synthesis of five novel half-sandwich Ir-(III) complexes incorporating benzo-[
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