Evidence map›Paper›PMID 42857557›Full record

ArticleCureus2026

Distribution of gyrA, rrs, and eis Gene Mutations Associated With Second-Line Drug Resistance Among Multidrug-Resistant Mycobacterium tuberculosis Isolates.

Rinku Yadav, Rosy Bala, Aparna Parmar, Narinder Kaur, Parminder Singh

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rinku YadavMicrobiology, Maharishi Markandeshwar Institute of Medical Sciences and Research (MMIMSR), Maharishi Markandeshwar (Deemed to be University), Ambala, IND.
Rosy BalaMicrobiology, Maharishi Markandeshwar Institute of Medical Sciences and Research (MMIMSR), Maharishi Markandeshwar (Deemed to be University), Ambala, IND.
Aparna ParmarMicrobiology, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, IND.
Narinder KaurMicrobiology, Maharishi Markandeshwar Institute of Medical Sciences and Research (MMIMSR), Maharishi Markandeshwar (Deemed to be University), Ambala, IND.
Parminder SinghMicrobiology, Maharishi Markandeshwar Institute of Medical Sciences and Research (MMIMSR), Maharishi Markandeshwar (Deemed to be University), Ambala, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrug-resistant tuberculosis (DR-TB) remains a major public health challenge, particularly with the increasing prevalence of resistance to second-line anti-tubercular drugs. Rapid detection of mutations associated with fluoroquinolone (FQ) and second-line injectable drug (SLID) resistance is essential for appropriate treatment selection and prevention of further drug resistance.

objectivesTo determine the genotypic patterns of second-line drug resistance among drug-resistant

methodsA cross-sectional study was conducted on 85 drug-resistant

resultsA total of 85 drug-resistant

Indexed as

drug-resistant tuberculosisfluoroquinolone resistancegenotype mtbdrslgyramdr-tbmolecular diagnosticspre-xdr tbrrssecond-line injectable drug resistance

Identifiers

PMID42857557
PMCPMC13650968

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.