Evidence map›Paper›PMID 42857544›Full record

ArticleACS organic & inorganic Au2026

Asynchronous Radical Addition-Coupled Two-Electron Transfer in P450-Catalyzed Arene Oxidation.

Zijian Chen, Yingqi Li, Xiaotian Zhang, Yong Wu, Hongyan Ren, Jiawei Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS organic & inorganic Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zijian ChenSchool of Chemistry and Materials Science, Ministry-of-Education Key Laboratory of Numerical Simulation of Large-Scale Complex System (NSLSCS), Nanjing Normal University, Nanjing 210023 Jiangsu, China.
Yingqi LiSchool of Chemistry and Materials Science, Ministry-of-Education Key Laboratory of Numerical Simulation of Large-Scale Complex System (NSLSCS), Nanjing Normal University, Nanjing 210023 Jiangsu, China.ORCID https://orcid.org/0009-0008-0608-1506
Xiaotian ZhangSchool of Chemistry and Materials Science, Ministry-of-Education Key Laboratory of Numerical Simulation of Large-Scale Complex System (NSLSCS), Nanjing Normal University, Nanjing 210023 Jiangsu, China.
Yong WuSchool of Chemistry and Materials Science, Ministry-of-Education Key Laboratory of Numerical Simulation of Large-Scale Complex System (NSLSCS), Nanjing Normal University, Nanjing 210023 Jiangsu, China.ORCID https://orcid.org/0000-0001-7440-2203
Hongyan RenSchool of Teacher Education, Nanjing Normal University, Nanjing 210023 Jiangsu, China.
Jiawei XuPhysical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3QZ, U.K.ORCID https://orcid.org/0000-0002-2732-086X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The P450-catalyzed arene oxidation reaction (e.g., arene hydroxylation) is considered to have an arene oxide (or epoxide) intermediate. The two-electron transfer in the formation of arene oxide has two pathways. The electrophilic addition mechanism is initiated by substrate-to-porphyrin electron transfer, followed by electrophilic addition led by an Fe

Indexed as

arene oxidationcurvature effectelectron transfer mechanismenzymatic catalysisP450 enzyme

Identifiers

PMID42857544
PMCPMC13650946

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.