Evidence map›Paper›PMID 42857469›Full record

ReviewCytoJournal2026

Immune checkpoint inhibitor-associated acute interstitial nephritis: Pathogenesis and heterogeneity.

Jiyang Jiang, Yuhan Zhou, Yao Yao, Liang Weng, Hui Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in CytoJournal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiyang Jiang *Department of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing, China.
Yuhan Zhou *Department of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing, China.
Yao YaoDepartment of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing, China.
Liang WengDepartment of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing, China.
Hui WangDepartment of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing, China.ORCID https://orcid.org/0000-0003-4007-7363

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint inhibitor (ICI)-associated acute kidney injury is a significant complication of cancer immunotherapy, with acute interstitial nephritis (AIN) being the most common pathological type. This review systematically elaborates on the core pathogenesis, spectrum of pathological heterogeneity, and the distinct immunological underpinnings of ICI-associated AIN (ICI-AIN). The typical mechanism of ICI-AIN involves abnormal activation of the adaptive immune system, activating resident autoreactive CD8

Indexed as

Acute interstitial nephritisCD8+ tissue-resident memory T cellsImmune checkpoint inhibitorPathogenesisPathological heterogeneity

Identifiers

PMID42857469
PMCPMC13650571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.