Evidence map›Paper›PMID 42857464›Full record

ArticleAsian journal of neurosurgery2026

Postoperative Analgesia in Lumbar Discectomy: Morphine vs. Dexamethasone-Soaked Epidural Gelfoam: A Randomized Controlled Trial.

Narender Kaloria, Manbir Kaur, Mayank Garg, Venkata Ganesh, Ankur Sharma, Priyanka Sethi, Jaskaran Singh Gosal, Ashwini Reddy, Shoban Babu Vartya, Pradeep Kumar Bhatia

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In one paragraph

Article in Asian journal of neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Narender KaloriaDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Manbir KaurDepartment of Anesthesia and Critical Care, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Mayank GargDepartment of Neurosurgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Venkata GaneshDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ankur SharmaDepartment of Anesthesia and Critical Care, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Priyanka SethiDepartment of Anesthesia and Critical Care, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Jaskaran Singh GosalDepartment of Neurosurgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Ashwini ReddyDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India.ORCID 0000-0002-1148-8633
Shoban Babu VartyaDepartment of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Pradeep Kumar BhatiaDepartment of Anesthesia and Critical Care, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study compared the analgesic efficacy of gelfoam-soaked epidural morphine with gelfoam-soaked epidural dexamethasone following lumbar discectomies as their clinical comparison is lacking. Materials and Methods: Sixty patients undergoing single-level lumbar discectomy surgeries were randomized either in group M (gelfoam-soaked epidural morphine, 3 mg) or in group D (gelfoam-soaked epidural dexamethasone, 8 mg) placed over the duramater before the closure. The primary objective was to compare the mean time to first rescue analgesia for 24 postoperative hours. The secondary objectives were pain intensity, total rescue analgesic requirement, and to look for any adverse event related to study drugs. Statistical Analysis: The primary outcome was analyzed using a two-tailed unpaired Results: The mean time to first analgesic (hours) in both the groups (M vs. D, 26 [12] vs. 19 [6], mean difference = 7 [95% confidence interval [CI], -8.2, 22, Conclusion: Gelfoam-soaked epidural morphine versus dexamethasone demonstrated no difference in mean time to first rescue analgesic following lumbar discectomy surgeries but gelfoam-soaked epidural morphine reduced the requirement of rescue analgesia in the first 24 postoperative hours compared with gelfoam-soaked epidural dexamethasone.

Indexed as

dexamethasonegelfoam soakedlumbar discectomymorphinepostoperative analgesiarescue analgesia

Identifiers

PMID42857464
PMCPMC13652621

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