ArticlePulmonary circulation2026
Quantitative Inferior T-Wave Inversion as a Marker of High Pulmonary Vascular Resistance and All-Cause Mortality in Patients Evaluated for Pulmonary Hypertension.
Article in Pulmonary circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Right heart catheterization defines pulmonary hypertension (PH) hemodynamics, but simple markers of pulmonary vascular load remain useful. Inferior-lead T-wave inversion (TWI) is seen in right ventricular pressure overload; its association with pulmonary vascular resistance (PVR) and prognosis is uncertain. We retrospectively studied a cohort of 98 patients who underwent electrocardiography (ECG), echocardiography, and right heart catheterization within 48 h from 2021 to 2023. Inferior TWI amplitudes in leads II, III, and aVF were measured as absolute values and summed. Associations with PVR, performance for PVR > 5 Wood units, and all-cause mortality were evaluated. Twenty-five patients (26%) had PVR > 5 Wood units. The inferior TWI sum correlated with PVR (
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