ArticleSafety and health at work2026
Occupational Solar UV Exposure and Skin Cancer: A Quantitative Framework for Individual Causal Attribution in Dermatology Practice.
Article in Safety and health at work, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Occupational solar ultraviolet radiation (UVR) exposure is a major risk factor for keratinocyte carcinomas in outdoor workers. Individual causal attribution for medico-legal purposes requires partitioning risk contributions between occupational exposure and individual susceptibility factors-a question distinct from population-level burden estimation. This study is primarily a quantitative/methodological application of FAIR to occupational UV-related skin cancer. Methods: This methodological framework study applies the FAIR approach (Filtering evidence, Association quantification, Individual partitioning, Reasoned interpretation) to occupational solar UVR and skin cancer. Meta-analyses (1995-2025) were reviewed and adjusted for phototype, sex, and immune status. Individual attribution was estimated using game-theory-based decomposition (Shapley values) and stochastic Monte Carlo simulation to propagate uncertainty. Preventive scenarios incorporated sector-specific compliance and long-term economic modeling. Results: Mean occupational causal shares were 35% for squamous cell carcinoma (SCC), 25% for basal cell carcinoma (BCC), 10% for melanoma, and 50% for actinic keratosis. The probability of exceeding the 20% medico-legal attribution threshold reached 85% for SCC and 75% for BCC. Prevention reduced expected cases by 10-15% and healthcare costs by 8-12%. Conclusions: The FAIR framework provides a transparent, reproducible approach for integrating epidemiological evidence with individual attribution. These quantitative thresholds support the clinical and medico-legal recognition of work-related skin cancers.
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