ArticleHealth science reports2026
Assessment of Knowledge and Attitudes Toward Potential Drug-Drug and Drug-Food Interactions and Associated Factors Among Health Care Professionals at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: A Cross-Sectional Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Aims: The increased likelihood of potential drug-drug interactions (PDDIs) and food-drug interactions (FDIs) is primarily attributed to the increasing use of multiple medications and the practice of taking medicines with food. Healthcare professionals' (HCPs') knowledge and attitudes toward PDDIs and FDIs play a critical role in ensuring patient safety and effective medication management. An increase in PDDIs and FDIs can compromise patient safety, decrease treatment efficacy, and increase healthcare costs. Therefore, this study aimed to assess the knowledge and attitudes toward PDDIs and FDIs, as well as associated factors, among HCPs at the University of Gondar Comprehensive Specialised Hospital. Methods: A cross-sectional study was conducted at the University of Gondar Comprehensive Specialized Hospital. Healthcare professionals' knowledge of PDDIs and FDIs was assessed using a self-administered questionnaire. To examine knowledge predictors, we conducted a regression analysis. Data analysis was done using SPSS version 27. Results: There were 328 HCPs involved in this study; 325 completed the study, with a 99.1% response rate; Conclusion: Based on the results of this study, a minority of HCPs demonstrated good knowledge of potential drug-drug interactions (30.5%) and food-drug interactions (32.0%), indicating notable gaps in knowledge.
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