ArticleIJU case reports2026
Spontaneous Rupture of a Small Chromophobe Renal Cell Carcinoma Presenting as Wunderlich Syndrome.
Article in IJU case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Chromophobe renal cell carcinoma rarely causes spontaneous renal hemorrhage and enhances weakly on computed tomography. We report a case in which the tumor was masked by a perirenal hematoma for 11 months. Case Presentation: A 46-year-old woman presented with spontaneous renal hemorrhage and no visible renal mass. Magnetic resonance imaging (MRI) at 6 months showed an enhancing lesion indistinguishable from organizing hematoma; because it was shrinking with the hematoma, observation was continued. At 11 months, the hematoma had resolved and a 25-mm solid mass remained. Partial nephrectomy revealed pT1a chromophobe renal cell carcinoma without necrosis or sarcomatoid differentiation. She remained recurrence-free at 5 years. Conclusion: This case demonstrates spontaneous rupture of a small tumor without aggressive pathological features. When the cause of spontaneous renal hemorrhage remains unclear, serial imaging should be considered until hematoma resolution to avoid missing an occult malignancy.
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