Trial reportFrontiers in neurology2026
Clinical efficacy evaluation of combined central and peripheral repetitive transcranial magnetic stimulation for elbow flexor (biceps Brachii) spasticity and upper limb motor function after stroke.
Trial report in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This randomized controlled trial aimed to evaluate the efficacy and temporal dynamics of a combined central and peripheral magnetic stimulation protocol, combining central (M1) and peripheral (Erb's point) stimulation with conventional rehabilitation, for post-stroke elbow flexor spasticity and motor function. Methods: One hundred eligible stroke patients with upper limb spasticity were randomly allocated to Group A ( Results: A clear phase-specific effect was observed. At 3 weeks, Group A demonstrated significantly greater reduction in MAS scores (2(2, 3) vs. 3(2, 3), Conclusion: A combined central and peripheral rTMS protocol integrated with conventional rehabilitation is effective in alleviating elbow flexor spasticity and improving motor function after stroke. The delayed-start design supports that the observed benefits are attributable to the rTMS intervention, although residual placebo effects cannot be fully excluded. The effects are phase-specific, with motor improvement maintained at 6 weeks and a complex temporal pattern of spasticity reduction, likely mediated by modulating cortical excitability and spinal motor neuron pool activity.
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